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Acid Reflux In Infants Treatment
How should Carnitine Deficiency be treated in infants?
My cousin's daughter has been diagnosed with Acid Reflux disease, some muscle diseases that the doctors don't know what they are yet and Carnitine Deficiency. She's on some meds for these problems. She has a Mic button in her stomach to eat with because she doesn't eat right. She throws up a lot and it comes out of her mic button as well. Can anyone tell me what the normal treatment for carnitine deficiency is??
I copy this abstract for you, from the UCSF, Children's Hospital Central California, 9300 Valley Children's Place, Madera, CA 93638, USA
Abstract Summary: Carnitine deficiency is a secondary complication of many inborn errors of metabolism. Pharmacological treatment with carnitine not only corrects the deficiency, it facilitates removal of accumulating toxic acyl intermediates and the generation of mitochondrial free coenzyme A (CoA). The United States Food and Drug Administration (US FDA) approved the use of carnitine for the treatment of inborn errors of metabolism in 1992. This approval was based on retrospective chart analysis of 90 patients, with 18 in the untreated cohort and 72 in the treated cohort. Efficacy was evaluated on the basis of clinical and biochemical findings. Compelling data included increased excretion of disease-specific acylcarnitine derivatives in a dose–response relationship, decreased levels of metabolites in the blood, and improved clinical status with decreased hospitalization frequency, improved growth and significantly lower mortality rates as compared to historical controls. Complications of carnitine treatment were few, with gastrointestinal disturbances and odour being the most frequent. No laboratory or clinical safety issues were identified. Intravenous carnitine preparations were also approved for treatment of secondary carnitine deficiency. Since only 25% of enteral carnitine is absorbed and gastrointestinal tolerance of high doses is poor, parenteral carnitine treatment is an appealing alternative therapeutic approach. In 7 patients treated long term with high-dose weekly to daily venous boluses of parenteral carnitine through a subcutaneous venous port, benefits included decreased frequency of decompensations, improved growth, improved muscle strength and decreased reliance on medical foods with liberalization of protein intake. Port infections were the most troubling complication. Theoretical concerns continue to be voiced that carnitine might result in fatal arrhythmias in patients with long-chain fat metabolism defects. No published clinical studies substantiate these concerns. Carnitine treatment of inborn errors of metabolism is a safe and integral part of the treatment regime for these disorders.
(This revised version was published online in August 2006 with corrections to the Cover Date.)
Hope this helps
matador 89
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Heartburn acid reflux or (GERD) gastro esophageal reflux can be a very painful condition especially when you do not realize what is happening. Maybe you ate or drank something and now all of a sudden you are experiencing pain in the throat a burning sensation or a horrible taste in your mouth.
Indigestion reflux and heartburn are very common symptoms. Most people treat them by taking antacid medications. This is a mistake. Drugs do not cure the problem they only provide a temporary symptomatic relief. That is why most patients take them daily for many years. There are natural ways to deal with the problem and to solve it once and for all.
If you suffer from acid reflux or heartburn you may be interested to know that an all natural acid reflux home remedy is what is in the 'Reflux Remedy Report.' If you feel like you have heartburn more than twice a week or if your heartburn gets worse if you lie down or bend over its possible that you do suffer from acid reflux disease. You may also be spending a ton of money on either over the counter or prescription medications in an effort to get rid of your pain. You probably know that all these medications taken on a daily basis can't be very good for you but maybe you aren't quite sure what you can do to cure your problem.
PPI drugs actually shut down the pumps that produce the stomach acid necessary to digest food. The human body cannot digest and assimilate food properly without stomach acid. It is an essential function of our physical anatomy. Stomach acid also keeps very dangerous bacteria which live in the stomach and intestines in check. One can only imagine what damage PPI drug addicts are doing to their bodies.
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